Product Name :
ZGPAT Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
dJ583P15.3 FLJ14972 G patch domain-containing protein 6 GPATC6 GPATCH6 KIAA1847 MGC44880 RP4 583P15.3 ZC3H9 ZC3HDC9 展开
Function :
Transcription repressor that specifically binds the 5′-GGAG[GA]A[GA]A-3′ consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human ZGPAT 431-531/531
Species reactivity:
Human, Mouse, Rat, Rabbit
Verify application:
WB, ELISA
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year.1346809-61-7 Chemical name Avoid repeated freeze/thaw cycles.(2-Fluoro-6-methylphenyl)boronic acid web The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃.PMID:33533291 When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
57 KDa
Positive control :
Widely expressed.