Product Name :
Transcription factor AP-2-alpha Recombinant Rabbit Monoclonal Antibody [PSH02-06]
Predicted band size :
48 kDa
Observed band size :
48 kDa
Synonyms:
Activating enhancer binding protein 2 alpha antibody Activating enhancer-binding protein 2-alpha antibody Activator protein 2 antibody AP 2 transcription factor antibody AP 2alpha antibody AP-2 antibody AP-2 transcription factor antibody AP2 antibody AP2 Transcription Factor antibody AP2-alpha antibody 展开
Function :
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5′-GCCNNNGGC-3′ and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within human TFAP2A aa 1-437 / 437.
Species reactivity:
Human
Verify application:
WB, IHC-P, IF-Cell
Coupling :
unconjugated
Clone number:
PSH02-06
RRID:
AB_3072877
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.Price of tert-butyl (5-bromopentyl)carbamate
Storage buffer solution:
PBS (pH7.2-Bromo-6-iodoaniline Chemscene 4), 0.PMID:33653215 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 48 kDa
Positive control :
HepG2 cell lysate, SiHa cell lysate, HepG2, human breast tissue.