Product Name :
RGS7 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
OTTHUMP00000037994 antibody Regulator of G protein signalling 7 antibody Regulator of G-protein signaling 7 antibody Regulator of G-protein signaling RGS7 antibody Regulator of G-protein signalling 7 antibody
Function :
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(o)-alpha is specifically enhanced by the RGS6/GNG5 dimer. May play a role in synaptic vesicle exocytosis. May play important role in the rapid regulation of neuronal excitability and the cellular responses to short-lived stimulations. PTM:Palmitoylated. PTM:Phosphorylation and subsequent interaction with 14-3-3 proteins inhibits GAP activity. Contains 1 DEP domain. Contains 1 G protein gamma domain. Contains 1 RGS domain. subunit:Heterodimer with GNG5. Interacts with RGS7BP, leading to regulate the subcellular location of the heterodimer formed with Gbeta5 (By similarity). Interacts with 14-3-3 protein Tau and SNAP25BP.Price of 2908-71-6
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
The antiserum was produced against synthesized peptide derived from human RGS7.870196-80-8 uses AA range:155-204
Species reactivity:
Human, Mouse, Rat
Verify application:
WB
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:33622763 Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
65 kDa
Positive control :
Brain,