Product Name :
RYR1 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
Arrhythmogenic right ventricular dysplasia 2 antibody ARVC2 antibody ARVD2 antibody Brain ryanodine receptor calcium release channel antibody Brain type ryanodine receptor antibody Cardiac muscle ryanodine receptor calcium release channel antibody Cardiac muscle type ryanodine receptor antibody CCO antibody Central core disease of muscle antibody HBRR antibody 展开
Function :
Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules. Repeated very high-level exercise increases the open probability of the channel and leads to Ca2+ leaking into the cytoplasm. Can also mediate the release of Ca2+ from intracellular stores in neurons, and may thereby promote prolonged Ca2+ signaling in the brain. Required for normal embryonic development of muscle fibers and skeletal muscle. Required for normal heart morphogenesis, skin development and ossification during embryogenesis.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide within Human RYR1 aa 1,354-1,403 / 5,038.
Species reactivity:
Human, Mouse
Verify application:
Dot Blot, IHC-P, FC
Coupling :
unconjugated
Clone number:
RRID:
AB_3069218
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃.1041026-70-3 manufacturer Avoid repeated freeze / thaw cycles.90396-00-2 Order
Storage buffer solution:
1*PBS (pH7.PMID:33666274 4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 565 kDa
Positive control :
Human fetal skeletal muscle tissue, mouse cerebellum tissue, mouse skeletal muscle tissue, rat skeletal muscle tissue, SiHa.